Projects


With our Helmholtz Imaging Projects, Helmholtz Foundation Model Initiative (HFMI) and third-party funded projects, we aim to initiate cross-cutting research collaborations and identify innovative research topics in the field of imaging and data science.

Helmholtz Imaging offers a funding line of Helmholtz Imaging Projects, striving to seed collaborations between centers and across research fields. They are a strong incentive to enable interdisciplinary collaboration across the Helmholtz Association and an incubator and accelerator of the Helmholtz Imaging network. 

In addition to our Helmholtz Imaging Projects, the Helmholtz Imaging team has secured external funding for third-party projects contributing their knowledge and expertise on cutting-edge imaging methodology. 

Join us in unlocking the limitless potential of Helmholtz Imaging!

Find out more about Helmholtz Imaging Project call in this summary.

Helmholtz Imaging Projects


This image shows simulation results comparing MWF mapping with single inversions of "T2-decay" data, "T2*-decay" data, and with joint inversion of both. The joint inversion is significantly closer to ground truth, as the second row shows.
 

JIMM2

3D Myelin Mapping with AI and Uncertainty Quantification

Changes in brain myelin are linked to many neurological diseases. This project aims to improve myelin water imaging, enabling more accurate and accessible diagnostics.
Decorative image, HI DIPLO
 

DIPLO

Paving the way from in situ plankton image data to a Digital Twin Ocean

This project will develop a user-friendly software platform to analyze plankton images independent of the instrument with which images were collected. This will help to compare data and create a common database, which is a critical step towards an image-based ecosystem component of a “Digital Twin Ocean”.
Visual to illustrate HI Project BrainShapes
 

BrainShapes

Laplace-Beltrami shape descriptors of brain structures: Comparative optimization and genetic dissection

The project explores the 3D structure of the human brain by creating a digital 'map' of the brain and examining its unique genetic properties, potentially linking genetic variations to brain disorders.

Helmholtz Foundation Model Initiative (HFMI) Projects


Image: NicoElNino on Shutterstock

The Human Radiome Project (THRP)

The Human Radiome Project (THRP) aims to drive a paradigm shift in medical research, providing novel insights into human health and disease through the power of AI. By integrating diverse radiological data, it seeks to enable groundbreaking advancements in personalized medicine, enhancing diagnostic accuracy and improving patient care.
decorative image
Image: NicoElNino on Shutterstock

Synergy Unit

The Synergy Unit amplifies the Helmholtz Foundation Model Initiative's impact by developing AI principles for diverse fields. Collaborating with HFMI projects, it focuses on knowledge sharing, community building, and representation to ensure the initiative's lasting influence.
Microcosmos of the Ocean by Klas Ove Möller, Hereon
Image: NicoElNino on Shutterstock

AqQua

AqQua aims to build the first foundational pelagic imaging model using billions of aquatic images worldwide. These images, spanning species from plankton, will help an AI classify species, extract traits, and estimate carbon content, offering key insights into biodiversity, ecosystem health, and the biological carbon pump's role in climate regulation.

UNLOCK – Benchmarking Projects


Visual for UQOB; Creating a benchmark dataset for object-detection and Uncertainty Quantification (UQ) in a multi-rater setting, to address annotation variability and AI model evaluation.
 

UQOB – Uncertainty Quantification in Object-detection Benchmark

Creating a benchmark dataset for object-detection and Uncertainty Quantification (UQ) in a multi-rater setting, to address annotation variability and AI model evaluation.
Visual for Pero; Addressing the lack of standardized, FAIR benchmark datasets in perovskite photovoltaics. Pero enables reproducible AI models for efficiency prediction, material classification, and defect detection, which are critical for industrial scaling of sustainable energy technologies.
Image: Photo: Markus Breig, KIT; illustration: Felix Laufer, KIT

Pero – Unlocking ML Potential: Benchmark Datasets on Perovskite Thin Film Processing

Addressing the lack of standardized, FAIR benchmark datasets in perovskite photovoltaics. Pero enables reproducible AI models for efficiency prediction, material classification, and defect detection, which are critical for industrial scaling of sustainable energy technologies.
Image: FZJ

AMOEBE: lArge-scale Multi-mOdal Microbial livE-cell imaging BEnchmark

Building a large-scale, FAIR benchmark for AI-driven analysis of microbial communities using time-lapse microscopy to advance understanding of microbial dynamics, ecosystem stability, and their role in health and biotechnology.

Third-Party Projects


Decorative image
 

Foundations of Supervised Deep Learning for Inverse Problems

Recently, deep learning methods have excelled at various data processing tasks including the solution of ill-posed inverse problems. The goal of this project is to contribute to the theoretical foundation for truly understanding deep networks as regularization techniques which can reestablish a continuous dependence of the solution on the data.
visual for third-party funded project UMDISTO
 

UMDISTO: Unsupervised Model Discovery

The project aims to develop novel methods for unsupervised multi-matching to map cellular-level correspondences in organisms like C. elegans.
Visual for BestMeta
 

BestMeta

Behavioral Standard Metadata

Developing metadata standards and FAIR analysis pipelines for Video Tracking Assays (VTAs) in toxicology and medical sciences