Projects


With our Helmholtz Imaging Projects, Helmholtz Foundation Model Initiative (HFMI) and third-party funded projects, we aim to initiate cross-cutting research collaborations and identify innovative research topics in the field of imaging and data science.

Helmholtz Imaging offers a funding line of Helmholtz Imaging Projects, striving to seed collaborations between centers and across research fields. They are a strong incentive to enable interdisciplinary collaboration across the Helmholtz Association and an incubator and accelerator of the Helmholtz Imaging network. 

In addition to our Helmholtz Imaging Projects, the Helmholtz Imaging team has secured external funding for third-party projects contributing their knowledge and expertise on cutting-edge imaging methodology. 

Join us in unlocking the limitless potential of Helmholtz Imaging!

Find out more about Helmholtz Imaging Project call in this summary.

Helmholtz Imaging Projects


Decorative image, HI AutoCoast
 

AutoCoast

Automatic detection of coastline change and causal linkage with natural and human drivers

Coastal erosion enhanced by climate change has become an increasing global threat, which requires rapid detection and reliable risk assessment. AutoCoast aims to provide advanced and reliable remote sensing-based AI tools to quantify coastline change rate at high-resolution and unravel the linkage between coastline change rate and natural and anthropogenic drivers at regional to global scale.
Decorative image explaining WeMonitor
Image: WeMonitor

WeMonitor

Satellite-based Earth observation to detect natural hazards

Satellite imagery makes it possible to detect spatio-temporal anomalies on the Earth's surface, including natural hazards such as landslides, deforestation, or the emergence of large waste dump sites. This project aims to use artificial intelligence to detect these changes at an early stage and to be able to monitor their progress.
Helmholtz Imaging Project cryoFocal, image for overview page
 

cryoFocal

3D Reconstruction from defocused cryo-EM images

This project explores how defocused images recorded with an electron microscope can be used to reconstruct the 3D structure of molecules inside cells. This method aims to enable faster and more cost-effective structural analysis of molecules to accelerate understanding of their functions and to design drugs against them.

Helmholtz Foundation Model Initiative (HFMI) Projects


Microcosmos of the Ocean by Klas Ove Möller, Hereon
Image: NicoElNino on Shutterstock

AqQua

AqQua aims to build the first foundational pelagic imaging model using billions of aquatic images worldwide. These images, spanning species from plankton, will help an AI classify species, extract traits, and estimate carbon content, offering key insights into biodiversity, ecosystem health, and the biological carbon pump's role in climate regulation.
Image: NicoElNino on Shutterstock

The Human Radiome Project (THRP)

The Human Radiome Project (THRP) aims to drive a paradigm shift in medical research, providing novel insights into human health and disease through the power of AI. By integrating diverse radiological data, it seeks to enable groundbreaking advancements in personalized medicine, enhancing diagnostic accuracy and improving patient care.
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Image: NicoElNino on Shutterstock

Synergy Unit

The Synergy Unit amplifies the Helmholtz Foundation Model Initiative's impact by developing AI principles for diverse fields. Collaborating with HFMI projects, it focuses on knowledge sharing, community building, and representation to ensure the initiative's lasting influence.

UNLOCK – Benchmarking Projects


Visual for Pero; Addressing the lack of standardized, FAIR benchmark datasets in perovskite photovoltaics. Pero enables reproducible AI models for efficiency prediction, material classification, and defect detection, which are critical for industrial scaling of sustainable energy technologies.
Image: Photo: Markus Breig, KIT; illustration: Felix Laufer, KIT

Pero – Unlocking ML Potential: Benchmark Datasets on Perovskite Thin Film Processing

Addressing the lack of standardized, FAIR benchmark datasets in perovskite photovoltaics. Pero enables reproducible AI models for efficiency prediction, material classification, and defect detection, which are critical for industrial scaling of sustainable energy technologies.
Image: FZJ

AMOEBE: lArge-scale Multi-mOdal Microbial livE-cell imaging BEnchmark

Building a large-scale, FAIR benchmark for AI-driven analysis of microbial communities using time-lapse microscopy to advance understanding of microbial dynamics, ecosystem stability, and their role in health and biotechnology.
Visual for ForestUNLOCK; Building the first consistent multi-modal single tree benchmark for forest structure and carbon stock assessments of the northern boreal forest
Image: Open white spruce forest with glacier in background in the Chugach Mountains, Alaska, US ©Stefan Kruse, AWI

ForestUNLOCK: A multi-modal Multiscale Benchmark Dataset for AI-Driven Boreal Forest Monitoring and Carbon Accounting

Building the first consistent multi-modal single tree benchmark for forest structure and carbon stock assessments of the northern boreal forest

Third-Party Projects


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FONDA: Dependability, Adaptability and Uncertainty Quantification for Data Analysis Workflows in Large-Scale Biomedical Image Analysis

The project aims to enhance infrastructures for machine learning (ML)-intensive DAWs in advanced biomedical imaging applications.
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Deep Learning based Regularization for Inverse Problems

This project aims to investigate the construction of regularization methods for ill-posed inverse problems based on deep learning and their theoretical foundations. Specific objectives include the development of robust and interpretable results, requiring the initial development of new concepts of robustness and interpretability in this context.
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Foundations of Supervised Deep Learning for Inverse Problems

Recently, deep learning methods have excelled at various data processing tasks including the solution of ill-posed inverse problems. The goal of this project is to contribute to the theoretical foundation for truly understanding deep networks as regularization techniques which can reestablish a continuous dependence of the solution on the data.