Projects


With our Helmholtz Imaging Projects, Helmholtz Foundation Model Initiative (HFMI) and third-party funded projects, we aim to initiate cross-cutting research collaborations and identify innovative research topics in the field of imaging and data science.

Helmholtz Imaging offers a funding line of Helmholtz Imaging Projects, striving to seed collaborations between centers and across research fields. They are a strong incentive to enable interdisciplinary collaboration across the Helmholtz Association and an incubator and accelerator of the Helmholtz Imaging network. 

In addition to our Helmholtz Imaging Projects, the Helmholtz Imaging team has secured external funding for third-party projects contributing their knowledge and expertise on cutting-edge imaging methodology. 

Join us in unlocking the limitless potential of Helmholtz Imaging!

The next call for Helmholtz Imaging Projects is OPEN until July 30, 2025. Find out more about the project call in this summary.

Helmholtz Imaging Projects


Decorative image, HI BENIGN
 

BENIGN

Biocompatible and Efficient Nanocrystals for Shortwave Infrared Imaging

The BENIGN project aims to enable non-invasive molecular imaging with cellular resolution in vivo at depths of several millimeters. This will be achieved using light from the shortwave infrared (SWIR) range (1000-2000 nm), which has less scattering and autofluorescence compared to the visible and near-infrared spectral range. Bright and targeted imaging agents are needed to fully exploit this range. The project will develop a new approach using lanthanide-based core-shell structures that emit light in the 1500-2000 nm range.
 

SyNaToSe

Leveraging Cross-Domain Synergies for Efficient Machine Learning of Nanoscale Tomogram Segmentation

The aim is to develop an adaptable algorithm that can be used to perform different tasks in data and image analysis without needing to be trained with new, laboriously annotated images for each separate task.
Decorative image, HI EMSIG
Image: Johannes Seiffarth, FZ Jülich

EMSIG

Event-driven Microscopy for Smart Microfluidic Single-cell Analysis

Microfluidic live-cell imaging (MLCI) unlocks spatio-temporal insights into population heterogeneity emerging from a single cell. EMSIG brings smart live-event detection capabilities to MLCI to facilitate the adaptive optimization of biological event resolution and autonomously counteracting deteriorating image qualities.

Helmholtz Foundation Model Initiative (HFMI) Projects


Image: NicoElNino on Shutterstock

The Human Radiome Project (THRP)

The Human Radiome Project (THRP) aims to drive a paradigm shift in medical research, providing novel insights into human health and disease through the power of AI. By integrating diverse radiological data, it seeks to enable groundbreaking advancements in personalized medicine, enhancing diagnostic accuracy and improving patient care.
decorative image
Image: NicoElNino on Shutterstock

Synergy Unit

The Synergy Unit amplifies the Helmholtz Foundation Model Initiative's impact by developing AI principles for diverse fields. Collaborating with HFMI projects, it focuses on knowledge sharing, community building, and representation to ensure the initiative's lasting influence.
Microcosmos of the Ocean by Klas Ove Möller, Hereon
Image: NicoElNino on Shutterstock

AqQua

AqQua aims to build the first foundational pelagic imaging model using billions of aquatic images worldwide. These images, spanning species from plankton, will help an AI classify species, extract traits, and estimate carbon content, offering key insights into biodiversity, ecosystem health, and the biological carbon pump's role in climate regulation.

Third-Party Projects


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SFB Transregio 154 – C06: Transport metrics for analysis and optimization of network problems

SFB TRR 154 is a project of the German Research Foundation (DFG) and combines integer-continuous methods, model adaptation, and numerical simulation, to analyze and optimize gas markets, infrastructure, and control of networks. The third funding period specifically focuses on the transition from natural gas to hydrogen.
visual for third-party funded project UMDISTO
 

UMDISTO: Unsupervised Model Discovery

The project aims to develop novel methods for unsupervised multi-matching to map cellular-level correspondences in organisms like C. elegans.
Two people standing in a computer center; COMFORT logo is integrated in the image
Image: Tim Roith

COMFORT

COMFORT aims to achieve breakthroughs in developing compact, flexible, and robust machine learning models for image, audio, and network data. In doing so, its application-oriented research program will advance the mathematical understanding of machine learning at the intersection of effectiveness and robustness.