Projects


With our Helmholtz Imaging Projects, Helmholtz Foundation Model Initiative (HFMI) and third-party funded projects, we aim to initiate cross-cutting research collaborations and identify innovative research topics in the field of imaging and data science.

Helmholtz Imaging offers a funding line of Helmholtz Imaging Projects, striving to seed collaborations between centers and across research fields. They are a strong incentive to enable interdisciplinary collaboration across the Helmholtz Association and an incubator and accelerator of the Helmholtz Imaging network. 

In addition to our Helmholtz Imaging Projects, the Helmholtz Imaging team has secured external funding for third-party projects contributing their knowledge and expertise on cutting-edge imaging methodology. 

Join us in unlocking the limitless potential of Helmholtz Imaging!

Find out more about Helmholtz Imaging Project call in this summary.

Helmholtz Imaging Projects


Visual for Helmholtz Imaging Project PlastoView
Image: PlastoView

PlastoView

Microplastic Detection with the PlastiScope

Water quality is essential for ecosystems and human health, yet it's increasingly threatened by microplastics. This project develops image-based methods for detecting both plankton and microplastics using a new low-cost, mobile system.
Decorative image, HI EMSIG
Image: Johannes Seiffarth, FZ Jülich

EMSIG

Event-driven Microscopy for Smart Microfluidic Single-cell Analysis

Microfluidic live-cell imaging (MLCI) unlocks spatio-temporal insights into population heterogeneity emerging from a single cell. EMSIG brings smart live-event detection capabilities to MLCI to facilitate the adaptive optimization of biological event resolution and autonomously counteracting deteriorating image qualities.
 

SyNaToSe

Leveraging Cross-Domain Synergies for Efficient Machine Learning of Nanoscale Tomogram Segmentation

The aim is to develop an adaptable algorithm that can be used to perform different tasks in data and image analysis without needing to be trained with new, laboriously annotated images for each separate task.

Helmholtz Foundation Model Initiative (HFMI) Projects


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Image: NicoElNino on Shutterstock

Synergy Unit

The Synergy Unit amplifies the Helmholtz Foundation Model Initiative's impact by developing AI principles for diverse fields. Collaborating with HFMI projects, it focuses on knowledge sharing, community building, and representation to ensure the initiative's lasting influence.
Microcosmos of the Ocean by Klas Ove Möller, Hereon
Image: NicoElNino on Shutterstock

AqQua

AqQua aims to build the first foundational pelagic imaging model using billions of aquatic images worldwide. These images, spanning species from plankton, will help an AI classify species, extract traits, and estimate carbon content, offering key insights into biodiversity, ecosystem health, and the biological carbon pump's role in climate regulation.
Image: NicoElNino on Shutterstock

The Human Radiome Project (THRP)

The Human Radiome Project (THRP) aims to drive a paradigm shift in medical research, providing novel insights into human health and disease through the power of AI. By integrating diverse radiological data, it seeks to enable groundbreaking advancements in personalized medicine, enhancing diagnostic accuracy and improving patient care.

UNLOCK – Benchmarking Projects


Visusal for SCHEMA;Metastases represent a significant exacerbation of tumor severity. If one could predict the likelihood of tumors metastasizing, this could inform treatment decisions to avoid or delay this outcome. SCHEMA develops a benchmark dataset of primary tumor samples and metadata on whether the tumor has metastasized at different time points after sampling. With this dataset, a challenge for machine learning scientists will be defined to build prognostic models for likelihood of tumors metastasizing, promoting innovation in prognostic modeling for a clinically relevant task.
Image: Hellmut Augustin, DKFZ (BSIC 2021 contribution)

SCHEMA – profiling Spatial Cancer HEterogeneity across modalities to benchmark Metastasis risk prediction

SCHEMA creates a benchmark dataset linking tumor samples with metastasis outcomes to enable machine-learning models that predict metastasis risk and support clinical decision-making.
Visual for Pero; Addressing the lack of standardized, FAIR benchmark datasets in perovskite photovoltaics. Pero enables reproducible AI models for efficiency prediction, material classification, and defect detection, which are critical for industrial scaling of sustainable energy technologies.
Image: Photo: Markus Breig, KIT; illustration: Felix Laufer, KIT

Pero – Unlocking ML Potential: Benchmark Datasets on Perovskite Thin Film Processing

Addressing the lack of standardized, FAIR benchmark datasets in perovskite photovoltaics. Pero enables reproducible AI models for efficiency prediction, material classification, and defect detection, which are critical for industrial scaling of sustainable energy technologies.
Image: FZJ

AMOEBE: lArge-scale Multi-mOdal Microbial livE-cell imaging BEnchmark

Building a large-scale, FAIR benchmark for AI-driven analysis of microbial communities using time-lapse microscopy to advance understanding of microbial dynamics, ecosystem stability, and their role in health and biotechnology.

Third-Party Projects


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FONDA: Dependability, Adaptability and Uncertainty Quantification for Data Analysis Workflows in Large-Scale Biomedical Image Analysis

The project aims to enhance infrastructures for machine learning (ML)-intensive DAWs in advanced biomedical imaging applications.
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SFB Transregio 154 – C06: Transport metrics for analysis and optimization of network problems

SFB TRR 154 is a project of the German Research Foundation (DFG) and combines integer-continuous methods, model adaptation, and numerical simulation, to analyze and optimize gas markets, infrastructure, and control of networks. The third funding period specifically focuses on the transition from natural gas to hydrogen.
Visual for BestMeta
 

BestMeta

Behavioral Standard Metadata

Developing metadata standards and FAIR analysis pipelines for Video Tracking Assays (VTAs) in toxicology and medical sciences